Pu·MA System

Automated 3D Cell-Based Assays

Ready to automate your 3D cell-based assay?

At Protein Fluidics we enable automated assays for 3D cell models, organoids or spheroids to achieve multifunctional profiling. We support applications such as oncology, neuroscience, drug discovery and metabolic disease research. By combining microfluidics, our proprietary design and 3D assay technology, we can help streamline your workflows.

Pu·MA System

The combination of Pu·MA System and 3D Flowchips enables the automated workflows. This system maintains the organoids in a unique sample chamber and allows easy media, metabolite or reagent exchanges for oncology, toxicity, or metabolomics research. This system can help you get multiple data points from one single assay workflow.

3D Assay Products

3D Assay Technology

Our proprietary microfluidic technology allows for precise control of fluid movement within the flowchips. The various protocol steps are executed via the touchscreen on the Pu·MA System.

Assay workflows enabled by our technology:

In situ supernatant sampling
Sequential drug addition
In situ lysis for metabolomics
Immunofluorescence workflow

Learn More

Publication

Disease Modeling with 3D Cell-Based Assays Using a Novel Flowchip System and High-Content Imaging.

Cromwell EF et al., SLAS TECHNOLOGY Mar 30, 2021 epub

Automated organoid assay workflow for imaging and in situ sampling

HepG2 spheroids treated with increasing Staurosporine; staining and in situ sampling

Pubmed Link

Featured Application

Immunofluorescence staining for biomarkers using magnetically bioprinted spheroids and
patient-derived organoids.
Register for the upcoming webinar on this topic.