Practical Microfluidics for Bioanalysis
The Pu·MA System – Pneumatically driven Microfluidic Assays
Protein Fluidics’ Pu·MA System is a practical and affordable benchtop instrument that automates a wide range of biochemical and cell-based assays. It is a truly open platform that integrates sophisticated microfluidic handling within your current laboratory workflow to deliver robust assays results that are easier and less expensive to run.
- Automated low-volume reagent transfers
- Compact system – fits on your bench or in your incubator
- Multiwell plate format – seamlessly integrates with liquid handlers and plate readers
- Reduces sample and reagent volumes to 10 – 20 μL
Valve-Less Fluidic Switching
The underlying technology is our Valve-less Fluidic Switching (VLFS) that provides complex fluid control on a simple flowchip. This patent-pending technology allows precise fluid control in a microfluidic device without the need of mechanical microvalves or integrated moving parts.
- Enables a broad range of cell-based, homogenous biochemical and heterogeneous immunoassays
- Programmable and automated flow switching and combinatorial mixing
- Uses hydrophobic barriers to control fluids – no integrated valves or pumps
Capillary Fluid Flow Control
How does it work?
Microfluidic flowchips are set up as a combination of Reservoirs (A,B,C & D) and Nodes (N) connected by channels. Hydrophobic barriers are used to keep fluids in desired wells. Pneumatic pressure gradients are applied to transfer fluid from one Reservoir to another via a Node. An example is shown below where two reagents are transferred to different wells through the same Node. Watch a movie of VLFS in action!
Protein Fluidics, Inc.
875 Cowan Road, Suite B,
Burlingame, CA 94010
+1 650 529 5080