Pu•MA Technology

Practical Microfluidics for Bioanalysis

The Pu·MA System – Pneumatically driven Microfluidic Assays

Protein Fluidics’ Pu·MA System is a practical and affordable benchtop instrument that automates a wide range of biochemical and cell-based assays. It is a truly open platform that integrates sophisticated microfluidic handling within your current laboratory workflow to deliver robust assays results that are easier and less expensive to run.

  • Automated low-volume reagent transfers
  • Compact system – fits on your bench or in your incubator
  • Multiwell plate format – seamlessly integrates with liquid handlers and plate readers
  • Reduces sample and reagent volumes to 10 – 20 μl

Featured Applications

Flowchip Tech

Valve-Less Fluidic Switching

The underlying technology is our Valve-less Fluidic Switching (VLFS) that provides complex fluid control on a simple flowchip. This patent-pending technology allows precise fluid control in a microfluidic device without the need of mechanical microvalves or integrated moving parts.

  • Enables a broad range of cell-based, homogenous biochemical and heterogeneous immunoassays
  • Programmable and automated flow switching and combinatorial mixing
  • Uses hydrophobic barriers to control fluids – no integrated valves or pumps

Capillary Fluid Flow Control


Capillary Fluid Flow Control

How does it work?

Microfluidic flowchips are set up as a combination of Reservoirs (A,B,C & D) and Nodes (N) connected by channels. Hydrophobic barriers are used to keep fluids in desired wells. Pneumatic pressure gradients are applied to transfer fluid from one Reservoir to another via a Node. An example is shown below where two reagents are transferred to different wells through the same Node. Watch a movie of VLFS in action!

VLFS Technology Figure

Featured News

December 4, 2018 Protein Fluidics partners with BioLegend to provide Assay Products
May 4, 2018 Protein Fluidics announces the Pu·MA system
October 1, 2016 Protein Fluidics moves into new headquarters in Burlingame, CA
April 6, 2016 Protein Fluidics closes Series seed round of investment

For Research Use Only. Not for diagnostic use. Protein Fluidics, Protein Fluidics Logo and Pu•MA System are registered trademarks of Protein Fluidics, Inc. in the United States and internationally. All rights reserved. © 2020 PROTEIN FLUIDICS, INC.