Drug response profiling of individual primary colorectal cancer tumoroids using a novel automation workflow and AI-assisted image analysis

This poster was presented at Cell Symposia: Engineering development and disease in organoids, 2024. We demonstrated an automated workflow to dispense and assay 3D cell models using the spheroONE and Pu·MA System® EC followed by AI-assisted image analysis.

• Spheroids and organoids are automatically sorted, isolated and dispensed into flowchips for downstream assays providing precise control over the size and number of spheroids.
• Assays and fluid exchanges are performed in a novel microfluidic device that protects the cell models and enhances precision and control of the assay steps.