Featured Webinar: 3D Cell Models in Disease Research

Translational Research in Liver Cancer

Dr. Renumathy Dhanasekharan (Stanford University)

Presented on November 15, 2023

Summary

The goal of Dr. Dhanasekharan’s research is to understand the molecular pathogenesis of liver cancer and identify biologically relevant prognostic biomarkers and molecular targets for therapy in patients with hepatocellular carcinoma (HCC). Her focus is to study: (1) Drivers of tumor dormancy and recurrence of hepatocellular carcinoma (HCC), (2) Drivers of metastatic tumor progression in HCC (3) Prognostic gene signature for HCC (4) Glycoproteomic biomarkers of HCC (5) Using tumor cell free DNA (cfDNA) as biomarkers for HCC (6) Tumor progression of HCC in Non-Alcoholic Steatohepatitis (NASH).

In this webinar she will present her research approach and give a glimpse into the data and latest studies in the field of hepatocellular carcinoma from her lab.

Dr. Renumathy Dhanasekharan (Stanford University)

Renumathy Dhanasekaran, MD is an Assistant Professor in the Division of Gastroenterology and Hepatology at the School of Medicine, Stanford University. Her primary research goal is to explore the molecular biology of liver cancer in order to identify novel biomarkers and molecular-targeted therapies and to understand the molecular mechanisms of liver cancer metastasis and dormancy. She plays an active role in the cancer genome atlas (TCGA) consortium effort to translate the knowledge gained from the study of genomics of liver cancer. She maintains a bio-repository of tissue and blood samples from patients with liver cancer and has also developed several patient derived xenograft (PDX) models for preclinical testing. Dr. Dhanasekaran is a recipient of the American College of Gastroenterology (ACG) Junior Faculty Career Development award and the NIH/NCI K08 career development award.

Read more about Dr. Dhanasekharan’s research on her lab website here