PuMA Technology

Practical Microfluidics for Bioanalysis

The PuMA System is a pneumatically driven microfluidic platform for immunoassays

The PuMA is a portable and affordable benchtop instrument that uses your existing reagents and materials. Our proprietary Valve-less Fluidic Switching (VLFS) technology reduces a typical 4-6 hour assay down to < 1 hour. Sample volumes are also reduced down to 1/10th of typical requirements. It runs off of a user-friendly interface and allows for easy data transfer with your existing plate reader instruments for data collection and analysis.

Valve-Less Fluidic Switching

Valve-Less Fluidic Switching (VLFS) is a patent pending technology that allows precise fluid control in a microfluidic device without the need of mechanical microvalves or integrated moving parts.  Benefits include:

  • Enables a broad range of immunoassays and other life science applications
  • Programmable & automated flow switching and combinatorial mixing
  • Compatible with injection molded thermoplastics for large scale production

How does it work?  Microfluidic flowchips are setup as a combination of Reservoirs (A,B,C & D) and Nodes (N) connected by channels.  Hydrophobic barriers are used to keep fluids in desired wells.  Pneumatic pressure gradients are applied to transfer fluid from one Reservoir to another via a Node.   An example is shown below where two reagents are transferred to different wells through the same Node.   Watch a movie of VLFS in action!

Workflow Compression

Flowchip Benefits

Featured News


April 6, 2016 Protein Fluidics closes Series seed round of investment

October 1, 2016 Protein Fluidics moves into new headquarters in Burlingame CA

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